摘要 :目的 研究白细胞介素6(IL-6)对照射小鼠脾淋巴细胞亚群自然杀伤活性的影响。 方法 BALB.C小鼠分为照射组、对照组和照射+IL-6组，采用Panning法从小鼠脾淋巴细胞中分离L 3 T 4 、Lyt 2 和B细胞，用 3 H-TdR释放实验检测脾淋巴细胞亚群自然杀伤活性。 结果 照射+IL-6组与对照组比较， 3 H-TdR释放量有显著性差异(P<0.01)。 结论 IL-6具有促进照射小鼠脾淋巴细胞亚群活性作用。

    关键词 :小鼠;分次照射;淋巴细胞;白细胞介素6;自然杀伤活性;K562;S180

    The effects of IL-6on the natural killing activity of spleen lymphocyte subsets in irradiated mice

    WANG Hong-bing，WANG Xu，LIU Yong-biao，et al

    (Department of Oncology，Affiliated Hospital of Xuzhou Medical College，Xuzhou，Jiangsu221002，China)

    Abstract:Objective To study the effects of IL-6on the natural killing activity of spleen lymphocyte subsets in irradiat-ed mice.Methods The spleen lymphocytes in irradiated mice were separated into L3T4 ......