膀胱肿瘤_____膀胱肿瘤；癌，移行细胞；Ki67

膀胱移行细胞癌组织肿瘤增殖核抗原Ki67的表达意义

http://www.100md.com 《第四军医大学学报》 2005年第8期

膀胱肿瘤,,膀胱肿瘤；癌，移行细胞；Ki67,抗原；免疫组织化学,1材料和方法,2结果,3讨论,【参考文献】

     Expression of Ki67 in transitional cell carcinoma of bladder

    WANG ChenZhuang1,WANG He1,ZHANG YunTao1,CHEN GuangSheng2,WANG Yong3

    1Department of Urology,2Department of Pathology,Xijing Hospital,Fourth Military Medical University,Xian 710033,China,3Department of Urology,Tangdu Hospital,Fourth Military Medical University,Xian 710038,China

    【Abstract】 AIM: To study the expression of Ki67 in transitional cell carcinoma of bladder (TCC) and to evaluate the significance of the relationship between tumor grade and cell proliferation.METHODS: Ki67 mAb and immunohistochemistry were used to examine the expression of Ki67 in 79 cases of TCC and 30 cases of normal paracarcinoma as control.RESULTS: Ki67 LI highly expressed in TCC and the Ki67 labeling index (Ki67 LI) in TCC was positively related to the tumor pathological grade,clinical stage and lymphoid node metastasis.CONCLUSION: Ki67 may be involved in the genesis,progress and metastasis of bladder cancer and can be used as an index in evaluating the ability of tumor cell proliferation as well as the prognosis in TCC. ......

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