门静脉和尾静脉注入小鼠骨髓干细胞向肝脏迁移的比较
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穆丽雅, 韩明子, 祁金锋
骨髓干细胞;移植;静脉穆丽雅,韩明子,祁金锋.门静脉和尾静脉注入小鼠骨髓干细胞向肝脏迁移的比较. 世界华人消化杂志2006;14(14)1408-1411 A、B两组肝脏冰冻切
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穆丽雅, 韩明子, 祁金锋, 哈尔滨医科大学附属第二医院消化科 黑龙江省哈尔滨市 150086黑龙江省自然科学基金项目, No. D200536
通讯作者: 穆丽雅, 150086, 黑龙江省哈尔滨市, 哈尔滨医科大学附属第二医院消化科. lqz321521@163.com
电话: 0451-86605143
收稿日期: 2006-04-06 接受日期: 2006-04-27
Comparison between numbers of bone marrow stem cells migrated to liver after infusion into portal vein and caudal vein
Li-Ya Mu, Ming-Zi Han, Jin-Feng Qi
Li-Ya Mu, Ming-Zi Han, Jin-Feng Qi, Department of Digestive Diseases, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China
Supported by the Natural Science Foundation of Heilongjiang Province, No. D200536
Correspondence to: Dr. Li-Ya Mu, Department of Digestive Diseases, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China. lqz321521@163.com
Received: 2006-04-06 Accepted: 2006-04-27
Abstract
AIM: To explore the amount of bone marrow mononuclear cells migrating to the liver during allografting in mice.
METHODS: Bone marrow stem cells were isolated from the bone marrow of mice by lymphocyte separation medium and labeled with PKH26. The labeled cells were subsequently infused into the caudal or portal veins of different mice with homogeneity, in which hepatic injury was induced by carbon tetrachloride and 2-acetylminofluorene ......
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