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自体血液回输对外伤性脾破裂切除术后免疫功能的影响
http://www.100md.com 《中华中西医杂志》 2006年第3期
自体血液,,外伤性脾破裂;自体血液回输;免疫功能,1资料与方法,2结果,3讨论,【参考文献】
     【摘要】 目的 研究自体血液回输对外伤性脾破裂切除术后免疫功能的影响。方法 应用流式细胞仪检测87例因外伤性脾破裂造成腹腔内出血患者,手术前后T细胞亚群CD3、CD4、CD8、CD4/CD8的变化并进行对比分析。结果 术后自体血液回输液CD3、CD4、CD4/CD8明显高于异体血液输入组(P<0.05),虽高于未予输血组,但差异无显著性(P>0.05);CD8明显低于异体血液输入组(P<0.05),与未予输血组相比,差异无显著性(P>0.05)。结论 自体血液回输有利于患者细胞免疫功能的恢复,应大力提倡自体血液回输。

    【关键词】 外伤性脾破裂;自体血液回输;免疫功能

    The impact of autologous blood transfusion on the immunological function of post-splenectomy for patients with traumatic splenic rupture

    CHEN Fen, WU Jian, SU Wen-li, et al. Department of Traumatic Surgery, The Putuo Hospital Affiliated to Shanghai Traditional Medicine University, Shanghai 200062,China

    【Abstract】 Objective To investigate impact of autologous blood transfusion on the immunological function of post-splenectomy for patients with traumatic splenic rupture. Methods The T lymphocyte subsets CD3,CD4,CD8,CD4/CD8 of 87 patients with traumatic splenic rupture were detected by FCM pre- and post-splenectomy, then the changes of data were analysed. Results The data of CD3,CD4,CD4/CD8 in autologous blood transfusion group were significantly higher than allo-blood transfusion group(P<0.05). Although it is higher than the group without blood transfusion, there is no significant difference(P>0.05).The data of CD8 are significantly lower than allo-blood transfusion group(P<0.05),but there is no significant difference to the group without blood transfusion(P>0.05). Conclusion Autologous blood transfusion is a helpful management to the recovery of immunological function in patients and should be generalized. ......

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