【摘要】 目的 观察生长抑素(施他宁)对重症急性胰腺炎的治疗作用。方法 以CT分级为D-E级重症急性胰腺炎42例随机分为治疗组(23例)和对照组(19例)，对照组常规联合加贝脂、法莫替丁、654-2治疗；治疗组使用施他宁治疗，观察两组中的症状、体征消失；血尿淀粉酶、白细胞计数、血糖、血钙变化情况及并发症情况。结果 两组患者发热、腹痛、腹胀、肌紧张、血尿淀粉酶、白细胞计数、血糖、血钙、胰外渗液等项指标的开始好转及恢复正常平均天数比较差异均有显著性(P<0.05)。结论 生长抑素能有效地治疗重症急性胰腺炎。

    【关键词】 重症急性胰腺炎；生长抑素；施他宁

    Determination the clinical efficacy of stilamin in severe acute pancreatitis in the gradation of CT D-E

    SUN Yu-hai，GU Qin，HAN Jiang,et al.Department of Surgery, Zhoupu Hospital of Shanghai Pudong, Shanghai 201318,China

    【Abstract】 Objective To determine the clinical efficacy of stilamin in severe acute pancreatitis.Methods Fourty-two patients with severe acute pancreatitis in the gradation of CT D-E were randomly divided into therapeutic group(n=23) and control group(n=19),Both stilamin,gabexate mesilate,famotidines and anisodaminum hydrochloride were administered for therapeatic group, Whereas only gabexate mesilate,famotidines and anisodaminum hydrochloride were used for contol group,the clinical symptoms and signs disappearing,blood amylase,urine amylase,white blood cell count,blood glucose,blood calcium and complications of the both groups was observed and compared.Results There was significanty difference between the two groups on average days of beginning recover and recover normal,fever,abdominal pain,peritoneal irritation sign, white blood cell count,blood glucose,blood calcium, urine amylase,extrinsic effusion of pancreas.Conclusion Stilamin appears significant effect on severe acute pancreatitis. ......