http://www.100md.com 《第四军医大学学报》 2005年第20期
骨肉瘤,,骨肉瘤；内皮生长因子；受体，生长因子，内皮，血管；微血管密度,1材料和方法,2结果,3讨论,【参考文献】Expression of vascular endothelial growth factor receptor KDR in osteosarcoma and its relationship with microvessel density
LIAO Bo1, MA BaoAn1, LIU Zhe2, FAN QingYu1
1Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xian 710038, China, 2Institute of Meteria Medical, Administration of Scientific Research, Fourth Military Medical University, Xian 710033, China
【Abstract】 AIM: To explore the expression of vascular endothelial growth factor receptor (VEGFR) KDR and its relation with microvessel density(MVD). METHODS: CD34 and KDR were investigated in the specimens from 102 osteosarcoma patients. MVD was determined with double blind counting. RESULTS: KDR was strongly expressed in osteosarcoma cells, and weakly expressed in vascular endothelial cells. MVD was significantly different between KDR negative and positive groups (P<0.05). CONCLUSION: High expression of KDR may be related to oeteosarcoma. ......
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