正交试验法优选雪胆素滴丸的成型工艺
雪胆素滴丸,,雪胆素滴丸；成型工艺；正交试验,1材料与仪器,2方法与结果,4讨论,参考文献:
摘要:目的 确定雪胆素滴丸的成型工艺。方法 以滴丸的硬度，外观，黏连为评价指标，采用正交试验法研究滴丸成型工艺的较优工艺条件。结果 工艺条件为：药物∶PEG4000∶PEG6000质量比为1∶1∶5，药料温度120 ℃，冷却剂的温度10 ℃，冷却柱长70 cm。 结论 通过上述试验确定的成型工艺合理，所制滴丸符合滴丸质量标准。关键词:雪胆素滴丸；成型工艺；正交试验
Preparation techniques of hemslein drop pills by orthogonal design
LIN Huaqing, ZHANG Shu,DENG Hong
(Institute of Materia Medica,Guangdong College of Pharmacy,Guangzhou 510006,China)
Abstract: Objective To optimize the preparation procedure of hemslein dropping pills.Methods All the procedures were evaluated for the hardness，appearance and stickiness of the pills，and optimized by orthogonal design.Results The best conditions were as follows: ration of hemsleinPEG4000PEG6000,1∶1∶5; temperature of drug,120 ℃; temperature of the refrigerant,10 ℃; length of the cool column,70 cm.Conclusion The optimized conditions are suitable for the preparation of hemslein dropping pills.
Key words:hemslein dropping pills; moulding techniques; orthogonal design
雪胆素 ......
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