卟吩_____卟吩;脱氢反应;叶绿素(期刊论文)

取代原焦脱镁叶绿酸a衍生物的合成

http://www.100md.com 《广东药学院学报》 2003年第1期

卟吩,,卟吩;脱氢反应;叶绿素,1实验部分,2结果与讨论,参考文献

     摘要目的：合成卟啉衍生物。方法：通过酸解反应从叶绿素a得到焦脱镁叶绿酸a，羧基保护后插入Zn2+形成金属配合物，采用2,3二氯5,6二氰1,4苯醌(DDQ)对C17C18氧化脱氢，然后脱去甲基，合成得到卟啉衍生物。结果：用DDQ脱氢氧化叶绿素系列化合物的C17C18单键形成双键，从而合成卟啉类化合物。结论：该方法条件温和、简便、副产物较少，是一个值得深入研究的方法。

    关键词卟吩;脱氢反应;叶绿素

    Synthesis of porphyrin derivative from pyropheophytina by 17,18-dehydrogenation

    LI Cuihua， ZHENG Jinghong， FANG Ye

    (Department of Chemistry,Medical College,Shantou University,Shantou,Guangdong515031)

    Abstract Objective：To synthesize porphyrin derivative. Methods: Pyropheophytina was obtained through acidic degradation from chlorophylla and then complexed with Zn2+. The obtained compound was dehydrogenated by DDQ. Results: The C17-C18single bond of chlorophylla was dehydrogenated with DDQ to form double bond, and the porphyrin derivative was obtained. Conclusion: DDQ is a good dehydrogenating oxidant. The reaction conditions are mild,simple and efficient.

    Key words dihydroporphin;porphyrin;dehydrogenation;chlorophyll a

    CLC number R914 Article ID:1006-8783(2003)01-0019-03 Document code:A

    叶绿素a是高等植物和藻类光合成的重要物质基础 ......

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