【摘要】 目的 探讨肯特令联合培菲康治疗腹泻型肠易激综合征(IBS)的临床疗效。方法 将90例患者随机分为三组，A组30例，予肯特令10g tid；B组30例，予培菲康630mg tid；C组30例，予肯特令10g tid，培菲康630mg tid。疗程均为8周。结果 A、B、C三组的临床有效率分别为56.7%、46.7%、93.3%，以C组最高，显著优于其他两组(P<0.01)。结论 肯特令联合培菲康是治疗腹泻型IBS的有效方法，疗效优于单药治疗。

    【关键词】 肠易激综合征；肯特令；培菲康

    Clinical observation of effects of combination of Smectite powder and Bifid Lriple Viable(BIFICO) on dirrhea-dominant irritable bowel syndrome

    YANG Xiu-hong.Department of Gastroenterology,Tinglin Hospital,Jinshan District,Shanghai 201505,China

    【Abstract】 Objective To study the clinical effects of combination of Smectite powedr and Bifid Lriple Viable on diarrhea-dominant irritable bowel syndrome.Methods 90 patients were divided into 3 groups randomly:group A included 30 cases were treated with Smectite powder 10g,3 times per day;group B included 30 cases were treated Bifid Lriple Viable 630mg,3 times per day;group C included 30 cases were treated with Smectite powder combined with Bifid Lriple Viable.The duration of treatment were all 8 weeks for 3 groups.Results The clinical effective rate was 56.7%、46.7%、93.3% in A、B、C group respectively.The highest effective rate was in group C and the difference was significant (P<0.01).Conclusion Combination of Smectite powder with Bifid Lriple Viable is an effective method for diarrhea-dominant irritable bowel syndrome,combination therapy can further improve the treatment effects. ......