【摘要】 目的：验证万拉法新治疗广泛性焦虑的疗效及不良反应。方法： 68例广泛性焦虑症按就医顺序分为两组，分别用万拉法新及阿普唑仑进行治疗，疗程6周，于治疗前及治疗后第1、2、4、6周末进行汉密顿焦虑量表(HAMA)、焦虑自评量表(SAS)、副反应量表(TESS)评定疗效及不良反应。 结果：万拉法新和阿普唑仑两药疗效相仿，万拉法新不良反应少而轻微。结论：万拉法新是治疗广泛性焦虑症较为理想的药物。

    【关键词 】 广泛性焦虑症；万拉法新；阿普唑仑

    A clinical control study of venlafaxine and alprazolam in the treatment of general anxiety disorder

    YU Hong-wei

    (Taian Mental Hospital of Demobilized Soldiers, Shandong 271000 , China)

    【Abstract】 Objective：To verify the clinical efficacy and the side effects of venlafaxine in the treatment of general anxiety disorder. Methods:68 patients were assigned to velafaxine group and alprazolam group respectively for 6 weeks. The efficacy and side effects were evaluated by HAMA, SAS and TESS before and after 1,2,3,4 and 6 weeks.Results: The efficacy of venlafaxine and alprazolam had no significant difference, but venlafaxine had fewer side effects.Conclusions: Venlafaxine is an effective and safe medicine in the treatment of general anxiety disorder.

    【Key words】Venlafaxine； Alprazolam； General anxiety disorder

    万拉法新是一种新型的抗抑郁药 ......