Establishment of animal model of selectively denervated masseter in rabbits

    DU Benª²Jun, LIU Daª²Lie, SU Bing, LIANG Li, LIU Yuª²Sheng, ZHENG Jianª²Sheng

    Department of Plastic Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China, 2Department of Clinical Laboratory, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China, 3Ultrasound Department, General Hospital of Chinese People¬ðs Armed Police Forces, Beijing 100089, China

    ¡¾Abstract¡¿ AIM: To design and establish the animal model of selectively denervated masseter, in order to provide experimental data and theoretical evidence for clinical surgery. METHODS: In a total of 105 experimental rabbits 5 rabbits were selected for masseter and nerve anatomy, and the others were randomly devided into 4 groups: Normal control group and 3 experimental groups (denervation of masseter nerve stem, of superior division of masseter nerve, and of inferior division of masseter nerve). In experimental groups, every rabbit served as its own control, that was, the right side was experimental side, and the left side was control side. The animal modle of selectively denervated masseter was established, and the thickness and weight of experimental masseter were compared with the normal¬ðs by the examination of B type ultrasound and electron equiª²armbalance.RESULTS: After the masseteric nerve hed been abscised, the thickness or weight of denervated masseter obviously became thinner or lighter. The thickness and weight of experimental masseter was changed to 50.77% and 54.01% of the normal¬ðs in group A, to 75.97% and 75.93% in group B , to 79.11% and 77.08% in group C. CONCLUSION: The animal model of selectively denervated masseter had been successfully set up for the first time. The thickness and humid weight of denervated masseter changed differently after different nerves were selected to be abscised. So, the model was available and credible, and was adapted to be used in researching denervated masseter in rabbits. ......