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推荐应用尿总蛋白/肌酐的诊断界线
http://www.100md.com 《东南国防医药》 2004年第6期
尿总蛋白,肌酐比;诊断界线;尿总蛋白;尿蛋白试条;测定单位,,]尿总蛋白,肌酐比;诊断界线;尿总蛋白;尿蛋白试条;测定单位,[摘要],[关键词],1材料与方法
     [摘要]目的探讨尿蛋白定性与定量不一致情况, 选择评价尿总蛋白测定单位及诊断界线。方法定性用罗氏10联试条。定量用邻苯三酚红法,Technicon RAXT自动生化仪测定。第1天晨尿尿蛋白定性,随后24小时尿总蛋白定量。结果尿蛋白定性阴性和轻度阳性以总蛋白/肌酐比(TPCR)200mg/g.Cr与总蛋白150mg/24h有相近阳性率。后者对尿量过多过少的儿童有误差,TPCR可避免儿童尿量过多过少的误差。讨论了尿总蛋白/肌酐比(TPCR)诊断界线200 mg/g.Cr各科的最新临床应用。结论尿总蛋白/肌酐比TPCR200mg/g.Cr实用、方便。

    [关键词]尿总蛋白/肌酐比;诊断界线;尿总蛋白;尿蛋白试条;测定单位

    A diagnosis criteria of urinary protein/creatinine ratio and it's clinical application

    HU Wangping, HU Yingying, HUANG Jingyao, et al. Clinical Chemistry Department,Fuzhou Genenal Hospital of PLA, Fuzhou 350025

    [Abstract]ObjectiveTo study all unanimous results between urine protein quantum and quality. To select analytical unit and diagnosis criteria.MethodsQualitative analysis was done with Roche Combur 10 Test M. Quantitative analysis was done with Pyrogallol Red protein dyebinding method on automatic assay urine total protein.ResultsIt was selected that total protein and creatinine ratio (TPCR) up to 200mg/g.Cr served as diagnosis criteria of proteinuria. However, there were overlap with routine examination of urine protein. There were false positive results qualitative of urine protein.TPCR positive rate was lower, but specificity higher than examination routine urine protein. There were the same positive rate between TPCR and up to 150mg/24h. It had been discussed that latest clinical applications of diagnosis criteria (200mg/g.Cr) of urinary protein/creatinine ratio in others subject.ConclusionsIt is utility and convenience that TPCR 200mg/g.Cr urine total protein. ......

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