儿童孤独症；局部脑血流灌注；放射性核素；99mTcECD

孤独症患儿局部脑血流灌注变化研究

http://www.100md.com 《临床心身疾病杂志》 2006年第2期

儿童孤独症；局部脑血流灌注；放射性核素；99mTcECD,,儿童孤独症；局部脑血流灌注；放射性核素；99mTcECD,【摘要】,【关键词】,1对象与方法,2

     【摘要】 目的评估孤独症患儿局部脑血流灌注的变化状况。方法对17例孤独症患儿与26例排除各种神经、精神疾病，头部CT或MRI检查均无异常的其它疾病患儿分别采用双探头单光子发射型计算机断层摄影仪和99mTcECD显像剂对两组进行局部脑血流灌注显像，以半定量方法分析脑内局部血流量的变化。结果孤独症患儿颞叶、尾状核、壳核、丘脑下部、海马、枕叶的血流量均存在不同程度的下降，与其它疾病患儿比较存在显著性差异(P<0.05)。结论 99mTcECD显像剂脑血流灌注显像对儿童孤独症的诊断和治疗有一定的帮助。

     【关键词】 儿童孤独症；局部脑血流灌注；放射性核素；99mTcECD

    Study on cerebral blood flow with 99mTcECD imaging for autistic children

    Du Yasong，Liu Yi，Yu Yongli，et al

    (Department of Child & Adolescent Psychiatry, Shanghai Mental Health Center, Shanghai 200030, China)

    【Abstract】 Objective To explore the clinical value of semiquantitative cerebral blood flow imaging in the diagnosis of children autism. Methods Total 1 7 cases diagnosed with autism were examined with cerebral blood flow imaging and 26 normal children were used as control.Semiquantitative analysis methods were used to estimate the changes of region cerebral blood flow.Results Comparing with normal children ......

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