术前合理营养支持对胃癌及结直肠癌患者术后恢复的影响
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姜英俊, 孔心涓, 程 广, 田字彬
肠内营养;肠外营养;消化道肿瘤;术前,姜英俊,程广,孔心涓,田字彬,通讯作者,Effectsofreasonablepre-operativenut
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姜英俊, 程广, 青岛大学医学院附属医院急诊普外科 山东省青岛市 266003
孔心涓, 田字彬, 青岛大学医学院附属医院消化内科 山东省青岛市 266003
通讯作者: 田字彬, 266003, 山东省青岛市江苏路16号, 青岛大学医学院附属医院消化内科. tianzb@qdumh.qd.sd.cn
电话: 0532-82911304 传真: 0532-82911111
收稿日期: 2006-04-24 接受日期: 2006-05-11
Effects of reasonable pre-operative nutrition on recoveries of gastrointestinal cancer patients
Ying-Jun Jiang, Xin-Juan Kong, Guang Cheng, Zi-Bin Tian
Ying-Jun Jiang, Guang Cheng, Department of Emergency General Surgery, the Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, Shandong Province, China
Xin-Juan Kong, Zi-Bin Tian, Department of Gastroenterology, the Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, Shandong Province, China
Correspondence to: Zi-Bin Tian, Department of Gastroenterology, the Affiliated Hospital of Qingdao University Medical College, 16 Jiangsu Road, Qingdao 266003, Shandong Province, China. tianzb@qdumh.qd.sd.cn
Received: 2006-04-24 Accepted: 2006-05-11
Abstract
AIM: To investigate the effects of pre-operative enteral and parenteral nutrition (EN-PN) on the malnourished gastrointestinal cancer patients.
METHODS: Sixty-nine malnutritional patients with gastrointestinal cancer were randomly divided into 3 groups: EN-PN group (n = 23), parenteral nutrition group (PN, n = 24) and non-nutrition group (NN,n = 22). EN-PN and PN group were received nutritional support of the same nitrogen and calorie 7 d before operation. Each group received the same nutritional support (EN-PN) 24 h after operation. The levels of serum albumin (ALB), pre-albumin (PA), transferrin (TFN), endotoxin (ET), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) were detected 7 d before and after operation. The levels of serum IgA, IgG and IgM, the activity of natural killer (NK) cells and the ratio of CD4 to CD8 (CD4/CD8) were measured to evaluate the immune function of the patients ......
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