草酸铂及羟基喜树碱联合亚叶酸钙和氟尿嘧啶治疗进展期结直肠癌的比较
http://www.100md.com
孙元珏, 赵 晖, 郭跃武, 林 峰, 蔡 讯,
草酸铂;羟基喜树碱;5-氟尿嘧啶;结直肠癌,孙元珏,赵晖,郭跃武,林峰,蔡讯,唐晓春,汤丽娜,姚阳,孙元珏,通讯作者,Clinical
 |
| 第6页 |
 |
| 第1页 |
参见附件(937KB，6页)。
孙元珏, 赵晖, 郭跃武, 林峰, 蔡讯, 唐晓春, 汤丽娜, 姚阳, 上海交通大学附属第六人民医院肿瘤内科 上海市 200233
孙元珏, 1998年上海医科大学本科毕业, 主治医师, 主要从事消化道肿瘤的内科治疗研究.
通讯作者: 姚阳, 200233, 上海市徐汇区宜山路600号, 上海交通大学附属第六人民医院肿瘤内科. yangyao_6@hotmail.com
电话: 021-64369181-8850
收稿日期: 2006-03-09 接受日期: 2006-04-30
Clinical study on combined chemotherapy of oxaliplatin or hydroxycamptothecine plus 5-fluorouracil and leucovorin for advanced colorectal cancer
Yuan-Jue Sun, Hui Zhao, Yao-Wu Guo, Feng Lin, Xun Cai, Xiao-Chun Tang, Li-Na Tang, Yang Yao
Yuan-Jue Sun, Hui Zhao, Yao-Wu Guo, Feng Lin, Xun Cai, Xiao-Chun Tang, Li-Na Tang, Yang Yao, Department of Medical Oncology, the Sixth People’s Hospital of Shanghai Jiaotong University, Shanghai 200233, China
Correspondence to: Dr. Yang Yao, Department of Medical Oncology, the Sixth People’s Hospital of Shanghai Jiaotong University, Shanghai 200233, China. yangyao_6@hotmail.com
Received: 2006-03-09 Accepted: 2006-04-30
Abstract
AIM: To evaluate the short-time efficacy, side effects, survival of combined chemotherapy of oxaliplatin or hydroxycamptothecine plus 5-fluorouracil and leucovorin for advanced colorectal cancer.
METHODS: Sixty patients with advanced colorectal cancer confirmed by pathology were included in this study. The patients in group A (n = 40) received oxaliplatin plus 5-fluorouracil and leucovorin, and those in group B (n = 20) were treated with hydroxycamptothecine plus 5-fluorouracil and leucovorin. Both regimens had 21-day cycle, i.e., the treatment was repeated once every 3 wk and the side effects were evaluated. The efficacy was estimated two or three cycles after chemotherapy.
RESULTS: The efficacy rates were 30.0% (12/40) and 25.0% (5/20) in group A and B, respectively, and there was no significant difference between them (χ2 = 0.531, P = 0.811). The 1-year survival rates (34.09% vs 38.55%, u = 0.3275, P > 0 ......
您现在查看是摘要介绍页，详见PDF附件(937KB，6页)。