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肾移植术后肺部真菌感染65例的诊断和治疗
http://www.100md.com 《东南国防医药》 2004年第1期
移植;肾手术;真菌感染,,]移植;肾手术;真菌感染,1资料与方法,2结果,3讨论,参考文献
     [摘要]目的探讨肾移植术后肺部真菌感染的诊断和治疗。方法分析1997年1月~2002年6月肾移植术后65例肺部真菌感染患者的临床资料。结果65例真菌感染中,白色念珠菌24例,克柔念珠菌6例,平滑念珠菌3例,曲霉菌6例,毛霉菌4例,新型隐球菌2例,奴卡菌3例,其中21例有细菌、巨细胞病毒混合感染。17例培养阴性。大扶康治愈33例,两性霉素B治愈27例,死亡5例。结论肺部真菌感染是肾移植术后的严重并发症,死亡率高。早期诊断和治疗可以防止真菌感染的发生。

    [关键词]移植;肾手术;真菌感染

    The diagnosis and treatment of fungal infections in lung after renal transplantation of 65 cases

    WU Yuanwen, LU Kequan, ZHOU Chenxi, et al. Department of Urological Surgery, the 101th Hospital of PLA, Wuxi 214044, Jiangsu, China

    [Abstract]ObjectiveTo study the diagnosis and treatment of fungal infections in lung after renal transplantation.MethodsTo analyze 65 cases of fungal infections in lung after renal transplantation from January 1997 to June 2002. ResultsAmong 65 cases, 24 were infected with candida albicans, 6 with mycormyccosis, 6 with aspergillum, 4 with mucor, 2 with cryptococcus neoformans and 3 with nocardia. 21 cases out of 65 cases were coinfected with bacteria and (or) CMV. 17 cases were negative. 33 cases were cured with fluconazole, 27 with amphotericin B and 5 died.ConclusionsFungal infection in lung is a severe complication after renal transplantation and has a high mortality rate. Early diagnosis and treatment may achieve satisfactory effects in preventing fungal infection. ......

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