【摘要】 目的 调查、分析我市城镇成年人群脂肪肝的患病率、发展趋势，同时试对脂肪肝危险因素进行Logistic回归分析，以进一步探求防治措施。方法 通过询问病史、生活史及既往史，测量身高、体重、血压，检测血脂、血尿酸、血糖、胰岛素、肝功能、华支睾吸虫抗体、肝脏B超等，收集2003～2005年连续3年来在我科健康普查的11956名成人的临床资料，进行临床医学统计处理和分析。结果 我市城镇成年人群脂肪肝患病率呈逐年上升趋势(由14.11%→16.33%→20.76%)，其中以20～39岁患病率上升较明显，患病率随年龄增长而上升，脂肪肝患者中肝功能异常率为28.5%，饮酒、肥胖、高甘油三酯血症、高胆固醇血症、糖尿病或糖耐量异常、高尿酸血症、高血压、华支睾吸虫病均为脂肪肝的危险因素，其中脂肪肝各危险因素按危险风险大小顺序排列如下：饮酒>肥胖>高甘油三酯血症>高胆固醇血症>糖尿病或糖耐量异常>高尿酸血症>高血压>华支睾吸虫病。结论 中山市城镇成年人群近3年来脂肪肝患病率呈上升趋势，并随着年龄增长而上升，有呈年轻化的趋势，而且与华支睾吸虫病发病呈相关性。

    【关键词】 脂肪肝；危险因素；Logistic回归分析

    Risk factors analysis of fatty liver disease by Logistic regression

    FENG Gen-yang,HE Wei-xiong,ZHONG Tu-li,et al.Boai Hospital of Zhongshan City,Zhongshan 518400,China

    【Abstract】 Objective To study diagnosis morbidity and trends of fatty liver disease in Zhongshan City,try to analysis risk factors of fatty liver disease by logistic regression and further explore prevention and control measures.Methods To know the diet and past history of disease,and measurements of height,weight,blood pressure,blood lipid,uric acid,glucose,insulin,liver function,hepatic distomiasis,liver B ultrasonic inspection etc.Collected 11,956 adults clinical information in Boai Hospital of Zhongshan City from 2003 to 2005.To discuss by medical and statistical processing.Results The morbidity of fatty liver disease upward trend (from 14.11%→16.33%→20.76%),while morbidity increased by more obvious in 20～39 years old.The morbidity of fatty liver disease upward trend growth rate increases,with no apparent gender differences.The rate is 28.5 percent of abnormal liver function in fatty liver disease,drinking,obesity,high triglyceride,high cholesterol,diabetes and the sugar tolerance unusual,hyperuricaemia,hypertension,hepatic distomiasis,all are the risk factors for fatty liver disease.These risk factors from large to small in the dangerous of fatty liver disease: drinking,obesity,high triglyceride,high cholesterol,diabetes and the sugar tolerance unusual,hyperuricaemia,hypertension,hepatic distomiasis.Conclusion The morbidity of fatty liver disease upward trend in Zhongshan City nearly three years,and the morbidity of fatty liver disease upward trend growth rate increases,There is a younger trend,fatty liver disease and hepatic distomiasis has relevance. ......