[摘要]目的研究肝硬化肝功能Child-Pugh A级患者合并急性有机磷农药中毒时血清胆碱酯酶(ChE)活力的变化以及对治疗预后的影响。方法对我院收治肝硬化肝功能Child-Pugh A级合并急性有机磷农药中毒48例患者动态监测胆碱酯酶的变化和预后之间的关系，并与对照组52例比较。结果 肝硬化肝功能Child-Pugh A级合并农药中毒组血清胆碱酯酶明显低于非肝硬化组，经治疗后血清胆碱酯酶恢复比非肝硬化组慢，且二组间的差异均有统计学意义，P<0.01。结论有机磷农药中毒患者的血清胆碱酯酶活力恢复的快慢与肝功能程度有关。

    [关键词]肝硬化;有机磷农药;血清胆碱酯酶;Child-Pugh分级

    The change of serum cholinesterase in patients with liver cirrhosis of Child-Pugh grade A and organophosphorus poisoning

    WANG limin，FU Wenan.Department of gastroenterology，The Shaoxing People's Hospital，Shaoxing312000，China

    [Abstract] Objective To analyze the change of serum cholinesterase(ChE)in hepatic cirrhosis of Child-pugh grade A combining organophosphorus poisoning patients and its influence to therapy and prognosis.Method The relationship of the change of ChE and prognosis was monitored dynamically in48hepatic cirrhosis incorporating with acute organophos-phorus poisoning patients selected and treated in hospital ......