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复方甘草酸苷对慢性重症肝炎患者肝脏储备功能的影响
http://www.100md.com 《汕头大学医学院学报》 2006年第2期
慢性重症肝炎;复方甘草酸苷;肝脏储备功能,,]慢性重症肝炎;复方甘草酸苷;肝脏储备功能,1资料与方法,2结果,3讨论,参考文献:
     [摘要]目的:了解复方甘草酸苷对慢性重症肝炎患者肝脏储备功能的影响。方法:100例慢性重症肝炎患者分为复方甘草酸苷组(治疗组50例。静滴复方甘草酸苷80mL/d,连续60d)和肝安组(对照组50例。静滴肝安250mL/d,连续60d);60d后检测两组肝功能指标及肝脏储备功能的变化。结果:治疗组肝脏储备功能较治疗前明显升高(P<005),与对照组比无统计学意义(P>005);两组肝功能指标均有改善(P<005)。结论:复方甘草酸苷能显著减轻肝脏损伤程度,提高其储备功能,且耐受性良好,无明显不良反应。

    [关键词]慢性重症肝炎;复方甘草酸苷;肝脏储备功能

    Effect of Compound Glycyrrhizin on Hepatic Function of Reserve in Patients

    with Chronic Fulminate Hepatitis

    LIN Chun_nuan, QIU Jie_wen, LI Ci_mei

    (Department of Infectious Diseases, The Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China) [Abstract]Objective: To understand the effect of compound glycyrrhizin on hepatic function of reserve in patients with chronic fulminate hepatitis. Methods: One hundren patients with chronic fulminate hepatitis were divided into treatment group(50 cases were injected chronic fulminate hepatitis of 80mL iv. drip, once a day, 60 days continuously)and control group(50 cases were injected 15AA of 250mL iv. drip, once a day, 60 days continuously). The changes of the liver function indices and the hepatic function of reserve were determinated 60 days after treatment. Results: Sixty days after treatment, the hepatic function of reserve in treatment group was higher(P<005). There was no statistically significance in hepatic function of reserve in treatment group, compared with control group. The liver function indices between two groups were improved(P<005). Conclusion: The compound glycyrrhizin can greatly reduce the damage of liver, and raise the hepatic function of reserve. There is a good toleration, and no obvious side effects have been found. ......

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