肝肿瘤·肝动脉·栓塞_治疗性·乙醇·射频消融_

TACE与TACE联合PEI、RF治疗肝脏转移癌的疗效比较

http://www.100md.com 《中国普通现代外科进展》 2006年第4期

肝肿瘤·肝动脉·栓塞,治疗性·乙醇·射频消融,,肝肿瘤·肝动脉·栓塞，治疗性·乙醇·射频消融,1材料与方法,2结果,3讨论,参考文献

     【摘要】目的：评价肝动脉化疗栓塞(TACE)与TACE联合经皮无水乙醇注射(PEI)或射频消融(RF)治疗肝脏转移癌的不同临床疗效。方法：67例肝转移癌分为单纯TACE组46例和联合治疗组21例(其中联合PEI组7例，联合RF组14例)。两组治疗结束后通过随访、CT复查及血液分析进行评价。结果：单纯TACE组的肿瘤总缩小率和肿瘤完全坏死率分别为46.8%和20.7%，联合治疗组分别为78.9%、49.2%(P均<0.05)，单病灶组、无转移灶组及联合治疗组的2年生存率高于多病灶组、有转移组和单纯TACE组(P均<0.05)。结论：综合介入治疗转移性肝癌较单纯TACE可以使病灶得到有效控制，减少肿瘤的复发或转移，延长患者的生存期。

    【关键词】肝肿瘤·肝动脉·栓塞，治疗性·乙醇·射频消融

    Comparison of the effect of TACE and TACE combined with PEI and RF on liver metastasis

    WANG Qingliang1,GUO Yiting2,LIU Haiyan3

    1Department of Radiology,Qilu Hospital of Shandong University(Jinan 250012,China)

    2Department of Radiology,Zaozhuang Third Hospital (Shandong 277100,China)

    3Department of Radiology,Taishan Sanatorium(Shandong 271000,China)

    【ABSTRACT】Objective:To evaluate the different effect of TACE and TACE combined with PEI and RF in treating liver metastasis.Methods：67 patients with liver metastasis were classified as group TACE(46 cases)and combined group including TACE+PEI(7 cases) and group TACE+RF(14 cases).All patients were analyzed after treatment by followup、CT and their blood biochemical tests.Results:The rate of tumor shrinkage and necrosis was 46.8% and 20.7%,while the contrast group was 78.9%,49.2% respectively(P<0.05).There were significant difference(P<0.05)for 2year survival rate in singlelesion group,nondistant metastasis group and combinedtherapy group.Conclusion:Comprehensive interventional therapy is effective in controlling lesions enlargement,reducing recurrent or distant metastasis and prolonging patients life in liver metastasis. ......

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