【摘要】 终末期肝病模型(model for end-stage liver disease，MELD)是主要应用血清胆红素、凝血酶原时间国际标准化比值和血清肌酐指标来评价终末期肝病的系统。其在预测终末期肝病死亡率及肝移植中的应用已渐趋成熟，应用范围也开始扩大到重型肝炎、肝癌中。文中对MELD作了回顾，并对最新进展进行阐述。

    【关键词】肝硬化；终末期肝病模型；移植；人工肝

    Model for end-stage liver disease and its applications in liver disease

    YU Hao，MA Hui.Department of Liver， People Hospital of Peking University， Beijing 100034，China

    【Abstract】 MELD score includes total of serum bilirubin， international normalized ratio (INR)， creatinine. The score system is exact to predict the mortality of chronic hepatitis and widely used pre-transplantation. Now it is applied to assess the severity of severe hepatitis and hepatocellular carcinoma. Many studies are still going on and maybe the score system will be more efficient with some modifications.

    【Key words】 liver cihrrosis;model for end-stage liver disease;transplantation;artificial liver

    终末期肝病一直以来都没有一个较完善的评分指标来评价其严重程度 ......