[摘要] 目的 探讨血浆血尿酸水平与冠脉病变程度的关系。方法 选择51例疑诊为冠心病并进行冠状动脉造影检查的病例，根据冠状动脉造影结果分为冠心病组(冠脉造影阳性30例)和非冠心病组(冠脉造影正常21例)。其中冠心病组单支病变13例，双支病变10例，三支病变7例。2组同时检测血脂各成分进行比较，最后分析血尿酸与冠脉病变程度的关系。结果 冠心病病人在体重指数、TG、TC、LDL、HDL方面与对照组差异无显著性(P>0.05)，冠心病合并高尿酸血症明显高于冠脉造影正常组(P<0.05)，病变冠脉支数差异有显著性(P<0.05)。结论 血尿酸水平与冠脉病变的严重程度是一致的，检测血尿酸水平有可能成为一项有价值的、能预测冠心病事件的常规检查方法。

     [关键词] 冠状动脉病变；高尿酸血症；冠脉血管造影术

    Study of the correlation between plasma urea acid the severity of coronary artery lesions

    ZHANG Li-gang,ZHANG Wan-rong,ZHANG Jun,et al.

    Department of Cardiology,Erdos Cardiocerebrovascular Disease Hospital,Inner Mongolia 017000,China

    [Abstract] Objective To investigate the correlation between plasma urea acid and coronary artery lesions.Methods 51 patients were divided into the control group (n=21) and the coronary artery heart disease (CHD) group (n=30),which included single vessel lesion (n=13),double vessel lesions (n=10) and triple vessel lesions (n=7) according to coronary angiography.At the same time the lipid components were examined and the relationship between UA and coronary artery lesions were analysed.Results Compared with the control,the total cholesterol (TC),low density lipoprotein cholesterol (LDL),triglyceride (TG) and high density lipoprotein cholesterol (HDL) were no difference in the CHD group,(P>0.05)there were significant difference in terms of plasma urea acid level between the CHD group and the control.The analysis showed that plasma urea acid were most directly correlated with the coronary artery lesions in the CHD group.Conclusion The result suggest the severity of coronary artery lesion correlated with plasma urea acid level,and plasma urea acid are indicators than other. ......