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连续血液滤过对重症急性胰腺炎的治疗作用
http://www.100md.com 《第四军医大学学报》 2006年第16期
血液滤过;急性病;胰腺炎,,血液滤过;急性病;胰腺炎,0引言,1对象和方法,2结果,3讨论,【参考文献】
     Curative effect of continuous venovenous hemofiltration in patients with severe acute pancreatitis

    CHEN JiaYu, ZHANG FangXin, WU HongMei, LIU LiHua, ZHAO Li

    Department of Digestive Diseases, Lanzhou General Hospital, Lanzhou Military Area Command, College of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, China

    【Abstract】 AIM: To observe the treatment effect of continuous venovenous hemofiltration (CVVH) in patients with severe acute pancreatitis(SAP). METHODS: Twentysix SAP patients were randomly divided into 2 groups: CVVH group (A, n=11) and control group (B, n=15). Both of group A and B were treated with conventional therapy, while the patients in group A additionally underwent CVVH. Heart rate (HR), respiration(R), blood pressure (BP), functions of liver, kidney and gastrointestine were observed. PO2/FiO2, SaO2, plasma levels of electrolyte and glucose, Creactive protein (CRP) and blood routine were determined. APACHEⅡ scores were used to evaluate the patients conditions. RESULTS: White blood cell(WBC), plasma levels of glucose and calcium were improved in group A and B 24 h after treatment (P<0.05). Group A was better than group B in terms of the functions of liver, kidney and APACHEⅡ scores (P<0.05). Seven days later, CRP was decreased in both A and B (P<0.05), but more distinctly in group A (P<0.05). B was also improved in the functions of liver, kidney and APACHEⅡ scores (P<0.05). The incidences of acute lung injury and complications were reduced significantly in the 2 groups (P<0.05). The hydrocele was removed rapidly in both chest and abdomen and the incidence of complications was decreased (P<0.05). CONCLUSION: CVVH may correct the liver and renal dysfunctions that were brought out by SAP, improve physical conditions, and prevent efficiently the complications. ......

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