加味柴芍承气汤对重症急性胰腺炎肺损伤的作用
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王国品, 滕晓琨, 杨 莉, 徐肇敏, 黄晓丽,
胰腺炎;肺损伤;柴芍承气汤;银杏叶;炎症介质王国品,滕晓琨,杨莉,徐肇敏,黄晓丽,王平,曾皓明.加味柴芍承气汤对重症急性胰腺炎肺损伤的作用. 世界华人消化杂志2006;14(26)2636
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王国品, 滕晓琨, 杨莉, 黄晓丽, 王平, 曾皓明, 东南大学附属南京江北人民医院消化科 江苏省南京市 210048
徐肇敏, 南京大学医学院附属鼓楼医院消化科 江苏省南京市 210008
南京市医学科技发展重点项目, No. ZKX0325
通讯作者: 王国品, 210048, 江苏省南京市大厂葛关路552号, 东南大学附属南京江北人民医院消化科. yywgp@263.net
电话: 025-86086708
收稿日期: 2006-06-30 接受日期: 2006-07-31
Effects of Chaishao Chengqi decoction with ginkgo biloba leaf on lung injury induced by severe acute pancreatitis
Guo-Pin Wang, Xiao-Kun Teng, Li Yang, Zhao-Min Xu, Xiao-Li Huang, Ping Wang, Hao-Ming Zeng
Guo-Pin Wang, Xiao-Kun Teng, Li Yang, Xiao-Li Huang, Ping Wang, Hao-Ming Zeng, Department of Gastroenterology, Nanjing Jiangbei People’s Hospital, Nanjing 210048, Jiangsu Province, China
Zhao-Min Xu, Department of Gastroenterology, Nanjing Gulou Hospital, Nanjing 210048, Jiangsu Province, China
Supported by Nanjing Science and Technology Development Keystone Program, No. ZKX0325
Correspondence to: Guo-Pin Wang, Department of Gastroenterology, Nanjing Jiangbei People’s Hospital, Nanjing 210048, Jiangsu Province, China. yywgp@263.net
Received: 2006-06-30 Accepted: 2006-07-31
Abstract
AIM: To explore the preventive and therapeutic effects of Chaishao Chengqi decoction (CCD) with ginkgo biloba leaf (GBL) on the lung injury induced by severe acute pancreatitis (SAP).
METHODS: A total of 65 SAP patients were divided into group A (n = 35) and B (n = 30). Besides internal treatment, the patients in group A also received CCD plus GBL. The occurrence of hypoxemia, duration of abdominal pain-relief, recovering time of borborygmus, local complications, and mortality rate as well as the level changes of serum platelet-activating factor (PAF), tumor necrosis factor-a (TNF-a), and interleukin-1 (IL-1) 72 h after treatment were observed, respectively. Upper abdominal spiral CT scanning was used to evaluate the degrees of severe acute pancreatitis ......
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