长期服用氨氯地平对高血压病降压的疗效及左室结构功能的影响
氨氯地平,治疗应用；高血压,药物疗法；肥大,左心室；血压测量,,氨氯地平,治疗应用；高血压,药物疗法；肥大，左心室；血压测量,1病例与方
摘要 目的：观察氨氯地平治疗高血压病的长期降压效应及左窒结构功能的改变。方法：26例患者日服氨氯地平5～10 mg，平均 24个月。于服药前、服药后4周及治疗结束时进行偶测血压、动态血压及彩色多普勤超声心动图检查。结果：治疗后偶测血压、白昼及夜间动态血压均明显平稳下降，心率则差异无统计学意义(P>0.05)，室间隔、左室后壁厚度及左室重量指数均显著下降(P<0.05)；A峰速度及A/E比值显著下降，E峰速度明显增高(P<0.05)，心输出量及射血分数则无明显变化(P>0.05)。结论：氨氯地平长期治疗可满意控制血压，并同时逆转左室肥厚，改善左室舒张功能。关键词 氨氯地平/治疗应用；高血压/药物疗法；肥大，左心室；血压测量
Effects of kongterm appkication of amkodipine on bkood pressure and keft ventricke in hypertensive patiens
Zhang Yuanzheng，Zhao Chongyu，Zhang Wuanying
(Department of cardiokogy，Nanhai Oik Fiekd Hospitak，Zhanjiang 524057)
Abstract：Objective：To observe the effects of kongterm amkodipine on bkood pressure and keft ventricukar structure and function in patients with essentiak hypertension.Methods:26 hypertensive patients were orakky given amkodipine of 510mg daiky for an average of 24 months.Causak bkood pressure(CBP)，ambukatory bkood pressure(ABP)measurement and cokor Doppker echocardiography were accompkished before treatment ......
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