【摘要】 目的 探讨E-CR1基因在鄂温克族及北方回族正常人群中基因多态性分布特点。方法 采用多聚酶链式反式—限制性片段长度多态性(PCR-RFLP)方法。结果 56例鄂温克族正常个体E- CR1基因多态性为：HH型(高表达)占69.64%，HL型(中表达)占30.36%，未检测到LL型(低表达)；57例回族个体E- CR1基因多态性为HH型占73.68%，HL型占24.56%，LL型占1.76%。结论 鄂温克族与回族的E- CR1基因多态性分布与汉族、蒙古族差异无显著性。本研究为北方地区少数民族的遗传免疫学研究提供了理论依据，也为人类学基因库积累了科学资料，同时也为临床许多疾病的发病机理研究提供重要的参考数据。

    【关键词】 红细胞免疫; 遗传多态性; PCR-RFLP; CR1; 基因

    The distribtion of polymorphsim in Ewenki nation in inner monglia and Hui nation in north population

    JIANG Li-ping, LIU De-bin, CUI Ming-yu,et al.Histology Embrology Teaching and Research Section，Inner Mongolia Medical College，Hohhot 010059, China

    【Abstract】 Objective To investigate the distribution of the erythrocyte complenent receptor 1(ECR1) gene polymorphism.Methods By the polymerase chain reaction(PCR)-restriction fragment length polymorhism(RFLP).Results The results detected to Ewenke healthy individuals were as follows：the HH(homozygous for high quantity CR1)gene type was 69.64 percent；the HL(homozygous for medium quantity CR1)type was 30.36 percent；and no LL(homozygous for low quantity CR1)type ......