[摘要] [目的] 探讨乙型肝炎病毒(HBV)前S1抗原检测在乙型肝炎诊断中的意义. [方法] 用ELISA法给163例不同类型乙型肝炎患者血清标本进行前S1抗原检测，并进行HBV-DNA定量测定，分析性别及民族与前S1抗原阳性的相关关系. [结果] 大三阳患者前S1抗原阳性率为95%，小三阳患者为51%;前S1抗原阳性与HBV-DNA阳性相符率为95%. [结论] 血清前S1抗原检测对乙型肝炎诊断有意义.

    [关键词] 乙型肝炎病毒;抗原，病毒;聚合酶链反应

    The significance of analysis of Pre S1detection on163cases of hepatitis patients

    ZHANG Yong-fen，JIN Xing-lin，JIN Chun-yan，SONG Ying-lan

    (Department of Laboratory Medicine，Affiliated Hospital of Yanbian University，Yanji133000，Jilin，China)

    ABSTRACT:OBJECTIVE To investigate diagnose value of Pre S1detection in patients with hepatitis B.METHODS Pre S1detection in the serum specimen of163cases of different type of hepatitis B were done by ELISA method ......