中西医结合治疗临床疑难病的应用 (pdf)

    【摘要】 1993年9月～2006年6月采用中药方剂结合西药治疗临床疑难病。中药结合不同剂量的联合化疗治愈70例中晚期癌症患者。40例病人获得长期生存，30例生存期超过5年，16例超过10年，最长者已15年。中药对中风、肾病综合征、风湿病痛及其他疑难病也有不可忽视的重要性。文中就药物的作用机制和维甲酸药物的作用原理进行讨论[受体蛋白的合成，JN Langley, 1878, Paul Ehrlich, 1900；和原瘤受体基因(即受体基因蛋白的致瘤)学说的发现，George Zhu, 1991，维甲酸药物作用的基因调控]。

    【关键词】 疑难病； 中西医结合； 药学机制;受体和原瘤受体；药物作用的基因调控

    An approach to the clinical study on Chinese traditional combined western medicine treatment for difficult diseases

    George Zhu. The Institute of Oncology of George Zhu,Shaoyang,Hunan 422407,China

    【Abstract】 From September 1993 to June 2006 Ⅰ was in detail proposed the Chinese traditional combined western medicine treatment in clinical trial.Seventy of various cancers had been successfully treated using combination chemotherapy with Chinese traditional medicine.Among those 40 long-tem survival,30 patients with advanced cancers were survival over 5 years,16 cancers were survival over 10 years,and the longest patient over 15 years.Traditional medicine also had its affirmative importance on apoplexy、nephrotic syndrome and rheumatic disease. Receptor protein synthesis (JN Langley 1878,Paul Ehrlich 1900) and proto-oncogenic receptor hypothesis (George Zhu,1991,VOA 1992,12:8) for its active mechanism and the princile of the action of the retinoic acid be also discussed. ......