天香丹;_稳定型心绞痛;_生活质量____

天香丹对冠心病稳定型心绞痛患者生活质量的影响及疗效分析

http://www.100md.com 《新疆医科大学学报》 2006年第11期

天香丹;,稳定型心绞痛;,生活质量,,天香丹;,稳定型心绞痛;,生活质量,1资料与方法,2结果,3讨论,参考文献:

     摘要: 目的: 观察中药天香丹治疗冠心病稳定型心绞痛患者的临床疗效及对患者生活质量的影响。方法: 156例冠心病稳定型心绞痛患者随机分为天香丹组(55例)、通心络组(50例)、消心痛组(51例)，3组均在抗血小板聚集、抗心肌缺血、调脂治疗的基础上分别口服天香丹颗粒、通心络胶囊、消心痛片进行治疗，疗程3个月，比较3组心绞痛、心电图及中医综合证候的改善情况，并采用健康状况调查问卷(SF36)及西雅图心绞痛量表(SAQ)评价患者的生活质量。结果：天香丹组、通心络组、消心痛组心绞痛治疗总有效率分别为81.82%、82.00%、72.58%,心电图总改善率分别为69.09%、74.00%、64.71%,3组差异均无统计学意义(P>0.05)，天香丹组、通心络组中医证候总改善率分别为85.45%、84.00%，明显优于消心痛组(P<0.05)。治疗后天香丹组与通心络组患者生理功能、生理职能、躯体疼痛、躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度方面的改善程度明显优于消心痛组(P<0.05)。天香丹组在改善患者精力方面明显优于通心络组与消心痛组(P<0.05)。结论：天香丹是治疗冠心病心绞痛的有效中成药，能减少心绞痛的发作，可以改善患者生活质量。

    关键词: 天香丹; 稳定型心绞痛; 生活质量

    Effect of Tianxiangdan on improving the quality of life in patients with angina pectoris

    Jaliken Tursun， AN Dongqing

    (Department of Cader′s ward, Affiliated Chinese Traditional Medical Hospital, Xinjiang Medical University, Urumqi 830054, China)

    Abstract: Objective： To evaluate the efficacy of Tianxiangdan Granule on improving the quality of life on stable angina pectoris patients. Methods: One hundred and fiftysix stable angina pectoris patients were randomized into 3 groups, All patients were received the antiplatelet aggregation, antimyocardial ischemia and lipidregulating drug treatment, 55 cases as Tianxiangdan group combined with Tianxiangdan Granule. 50 cases as Tongxinluo group combined with Tongxinluo Capsule and another 51 cases as Xiaoxintong group combined with isosorbide dinitrate tablet (IDT). One courses of treatment were lasted for 3 months and the following were compared to evaluated the clinical effects: clinical symptoms of angina, EKG reading, Chinese medical symptoms, survey Sf36 of the patients′ health and Seattle's angina SAQ indicator. Results: The difference of curative effect of angina pectoris and EKG between the three groups were not significant (P>0.05). The curative effect of Chinese medical symptoms of the Tianxiangdan and Tongxinluo group′s were better than IDT group (P<0.05) and the patients physical functioning (PF), Roal physical (RP), bodily pain (BP), physical limitation (PL), angina stable (AS), angina frequency (AF) and treatment satisfaction (TS) were also better than those in IDT group (P<0.05). The vitality (VT) of Tianxiangdan group were better than the other groups (P<0.05). Conclusions: Tianxiangdan is an effective Chinese patent medicine in the treatment of stable angina pectoris ......

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