[摘要] 目的 讨论人乳头瘤病毒(HPV)各亚型感染与宫颈上皮内瘤变(CIN)及亚临床感染(SPI)的关系。方法 应用电子阴道镜、宫颈多点病理活检、宫颈黏液刮片杂交捕获DNA分析(HC)方法筛查门诊及住院患者的HPV感染者，统计其中CIN的例数，并分级加以比较。结果 在SPI和CIN各期中，HPV各亚型的检出率均很高，但检出率无显著差异。结论 广泛筛查有性生活经历的女性对治疗SPI和CIN以预防宫颈癌有重要的指导意义，且电子阴道镜加多点病理活检加杂交捕获DNA分析可能是诊断率较高，误诊、漏诊率较低的方法。

    [关键词] 宫颈上皮内瘤变；电子阴道镜；亚临床病变

    Evaluation on relationship between cervical intraepithelial neoplasia and some subtypes of HPV infection

    JIN Ling，JIN Yan.Department of Gynecology,Tumor Hospital,Jilin City,132001，China

    [Abstract] Objective To evaluate the relationship between some subtypes HPV infection and cervical intraepithelial neplasia(CIN)and sub clinical papillomavirus infectron(SPI).Methods Apply the electron colporscopy,hybrid capture DNA analysis(HC),multi-points biopsy,and immunohistochemistry methods to exam the out-patients and in-patients,and compared the results by grades.Results In SPI or every grade of CIN cases,many subtypes of HPV are positive and the positive rate are very high,but the positive rate have no difference significantly.Conclusion It is very important to exam the HPV infection among the women who were not virgin by EC,HC and biopsy,and maybe a kind of useful method. ......