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Drug Induced Movement Disorders
http://www.100md.com 《新英格兰医药杂志》
     Is tardive dyskinesia disappearing with the use of second-generation neuroleptic agents? Is interest in studying this disorder declining? These and other thought-provoking questions are skillfully addressed in this second edition of Drug Induced Movement Disorders. Better than the successful first edition, this book thoroughly reviews the varied symptomatology, pathophysiological mechanisms, and treatments of movement disorders caused by commonly used psychiatric agents (such as neuroleptics, antidepressants, and lithium) and neurologic agents (such as dopaminergics and antiepileptics).

    This second edition, which appears 13 years after the first publication, is well timed and appreciated. Despite the claim that second-generation neuroleptic agents cause less parkinsonism than their predecessors, drug-induced movement disorders are here to stay; these agents are used more frequently than ever. Stewart Factor, Anthony Lang, and William Weiner are to be congratulated on assembling a cadre of neurologists and psychiatrists who have written scholarly reviews of this neglected but important topic.

    The book is easy to follow, clearly written, and succinct, and its chapters are well referenced. For these reasons, it should serve well as a primer for clinicians wanting to learn how to recognize, prevent, and treat drug-induced movement disorders, and it should aid them nicely in the judicious selection of antipsychotic and antidepressant agents. One of the primary strengths of the book is that it allows nonspecialists and psychiatrists to understand easily the phenomenology of complex movement disorders (tics, parkinsonism, and tremors) caused by current treatments, and it helps to differentiate these from other neurologic and psychiatric disorders. This book is an excellent reference for neurologists and specialists in movement disorders because of its comprehensive analysis of the symptomatology of the various movement disorders induced by commonly used drugs. As with any book with multiple contributors, there is some redundancy, and some chapters are not as strong as others. There are also some typographical errors. Despite these minor drawbacks, Drug Induced Movement Disorders will be an excellent addition to any medical library.

    Irene Litvan, M.D.

    University of Louisville

    Louisville, KY 40202

    i.litvan@louisville.edu(Second edition. Edited by)