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Kidney Disorders in Children and Adolescents: A Global Perspective of Clinical Practice
http://www.100md.com 《新英格兰医药杂志》
     Pediatric nephrologist Ron Hogg has gathered contributors from the international community of pediatric nephrology — some of whom have been instrumental in the development of this subspecialty — to examine the field in the context of recent clinical advances. These advances should be understandable to a wide audience of students and physicians. Advances in our understanding of the development of the kidney, the genetics of renal disease, the mechanisms of progressive kidney failure, and the adverse effects of chronic renal failure have improved the clinical evaluation and therapeutic approaches to the care of children with kidney disorders. In addition, there are new challenges of renal-replacement therapies for children, including that of preserving long-term kidney function in patients with transplants.

    In this comprehensive textbook, each of the 22 chapters follows a common theme of presenting information on diagnosis, evaluation, and treatment. The text, accompanied by easily understood tables and algorithms, reflects current thinking about epidemiology, mechanisms, diagnosis, evaluation, medical treatment, and the multidisciplinary management of kidney conditions in pediatrics.

    The excellent introduction gives an account of normal renal function, the development of the kidney, and laboratory studies in children. Information on new aspects of renal imaging, with an emphasis on the relationship between structure and function, congenital genitourinary anomalies, urinary tract infection, and vesicoureteral reflux, is presented clearly. The chapters on chronic kidney disease include the new guidelines for staging renal failure; they also cover immunization, endocrine and growth disturbances, current management, and nutritional and antimicrobial recommendations. The material on acute renal failure, hypertension, and renal transplantation bridges the gap between the child's first provider of care and the specialist. The chapters on screening for kidney disease, the molecular genetics of tubular disorders, and the transition of children with renal disease into adulthood are the most up-to-date sources of information in these areas.

    Frederick J. Kaskel, M.D., Ph.D.

    Children's Hospital at Montefiore

    Bronx, NY 10467

    fkaskel@aecom.yu.edu(Edited by Ron Hogg. 266 p)