[摘要] 目的: 探讨23价肺炎球菌多糖疫苗在支气管扩张患者的临床意义。 方法: 通过对28例支气管扩张患者注射23价肺炎球菌多糖疫苗后1年内肺部感染发生率及再发肺部感染的相距时间与对照组进行对比回顾性分析。 结果: 28例支气管扩张病例中在注射23价肺炎球菌多糖疫苗后1年内5例(17.85%)，对照组35例支气管扩张病例1年内16例(45.70%)再发肺部感染，两者比较有显著性差异(P<0.05)。治疗组再发肺部感染相距时间为(168±92)d;对照组再发肺部感染相距时间为(157±94)d;两者比较无显著性差异(P>0.05)。 结论: 23价肺炎球菌多糖疫苗能有效地减少支气管扩张患者肺部感染复发率，是临床佐治支气管扩张患者的一个有效方法，值得临床推广。

    [关键词] 23价肺炎球菌多糖疫苗;支气管扩张;临床观察

    Clinical observation on the application of23-valent

    pneumococcus polysaccharide vaccine in bronchiectatic patients

    LU Shu-biao，LU Wen-hui，RONG Fu

    (Department of Respiratory Medicine，the First People's Hospital，Shunde District，Fuoshan528300，China)

    Abstract:Objective:To investigate clinical significance in the application of23-valent pneumococcus polysaccharide vaccine in bronchiectatic patients.Methods:A retrospective analysis was made on the incidence rate of pulmonary infection and the interval of recurrent pulmonary infection through a clinical study of28patients with bronchiectasis one year after injection of23-valent pneu-mococcus polysaccharide vaccine.Results:Of the28cases of bronchiectatic patients who were injected with23-valent pneumococcus polysaccharide vaccine ......