[摘要]目的 了解特比奈芬对皮肤致病性产孢丝状真菌的敏感性与稳定性。方法 对73株产孢丝状真菌菌落作研磨处理后制备菌液，采用NCCLS M38-A方案微量稀释药敏试验法，检测特比奈芬对产孢丝状真菌的最小抑菌浓度(MIC)。结果 特比奈芬对红色毛癣菌MIC为0.001～0.060 mg/L，须癣毛癣菌为0.002～0.015 mg/L，絮状表皮癣菌为0.001～0.008 mg/L，未发现有耐药菌株。结论 特比奈芬对皮肤癣菌具有良好的抑制作用，NCCLS M38-A方案检测产孢丝状真菌具有结果稳定、重复性好的优点。

    [关键词] 特比奈芬;真菌;皮肤;微生物敏感性试验

    SUSCEPTIBILTY TESTING OF ANTIFUNGAL DRUG: TERBINAFINE AGAINST COMMON DERMATOPHYTES

    WANG XIAO-JIAN， QIANG XIN

    (Department of Microbiology， Qingdao University Medical College， Qingdao 266021，China)

    [ABSTRACT]ObjectiveTo evaluate the susceptibility and stability of terbinafine against common dermatophytes. Me- thodsSuspension of conidia prepared by grinding colonies of dermatophytes was used via M38-A method recommended by NC-CLS. ResultsIsolates of dermatophytes tested were highly susceptible to terbinafine ......