【摘 要】 目的 观察生兴化瘀汤对荷H 22 (A-S型)及S 180 (A-S型)小鼠肿瘤的影响。 方法 取H 22 及S180 腹水瘤接种于小鼠右腋皮下，随机分为模型对照组、环磷酰胺组(25mg.kg)和生兴化瘀汤26mg.g、13mg.g、6.5mg.g组，连续给药10d后剖瘤称重，计算肿瘤抑制率。 结果 生兴化瘀汤(生药)26mg.g组对荷H 22 小鼠肿瘤抑制率>30%;生兴化瘀汤26mg.g、13mg.g、6.5mg.g组对荷S180 小鼠肿瘤抑制率>30%。 结论 生兴化瘀汤对荷H22 小鼠肿瘤和荷S 180 小鼠肿瘤有明显抑制作用。

    【关键词】 生兴化瘀汤;环磷酰胺;H22 ;S180 ;肿瘤抑制率

    Study on the Tumor Inhibitory Effect of Shengxinghuayu Decoction on the H 22 -bearing and S 180 -bearing Mice SHI Tinglan，YANG Xue，RAN Changqing.Department of Pharmacology，Chongqing Academy of Chinese Material Medica，Chongqing400065，China

    【Abstract】 Objective To study the inhibitory effect of Shengxinghuayu decoction on murine transplanted hepatocarcinoma22(H 22 )and murine transplanted sarcoma180(S 180 )in vivo.Methods Tumor inhibitory activities were tested in experimental tumor(H 22 and S 180 )mice.The tumor bearing mice were randomly divided into control group ......