The long term clinical course of acute deep vein thrombosis of the arm: prospective cohort study
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《英国医生杂志》
1 Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University Hospital of Padua, Via Ospedale Civile 105, 35128 Padua, Italy, 2 Center for Vascular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands, 3 Department of Clinical Epidemiology and Technology Assessment, University of Maastricht, PO Box 5800, 6202 AZ Maastricht, Netherlands
Correspondence to: P Prandoni paoloprandoni@tin.it
Introduction
Symptomatic deep vein thrombosis of the arm carries a low risk of recurrent thromboembolism. Post-thrombotic sequelae occur in almost one fourth of patients within the first two years and are related to residual thrombosis and, to a lesser degree, to the extent of the initial thrombosis. The rates of recurrent thromboembolism and post-thrombotic syndrome are lower than those observed in cohorts of patients with venous thrombosis of the leg.4 Whether the incidence of long term sequelae might be further reduced by physical devices or other methods is worth investigating.
An additional table showing outcomes in patients with and without vein catheters is on bmj.com
This article was posted on bmj.com on 15 July 2004 http://bmj.com/cgi/doi/10.1136/bmj.38167.684444.3A
Contributors: PP, AWAL, AG, and EB conceived and designed the study. PP, AWLA, MHP, and EB drafted the article. MHP and AM offered their statistical expertise for analysing and interpreting data. PP, SV, PB, DS, AP, and PS provided study patients and collected data by following them prospectively over years. AG, AP, AM, and PS critically reviewed the article for important intellectual content. All authors approved the final version of the article. PP is guarantor.
Funding: None.
Competing interests: None declared.
Ethical approval: Institutional Review Board of Padua University.
References
Prandoni P, Polistena P, Bernardi E, Cogo A, Casara D, Verlato F, et al. Upper extremity deep-vein thrombosis risk factors, diagnosis, and complications. Arch Int Med 1997;157: 57-62.
Kommareddy A, Zaroukian MH, Hassouna HI. Upper extremity deep venous thrombosis. Semin Thromb Hemost 2002;28: 89-99.
Prandoni P, Lensing AWA, Cogo A, Cuppini S, Villalta S, Carta M, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996;125: 1-7.
Kahn SR, Hirsch A, Shrier I. Effect of post-thrombotic syndrome on health-related quality of life after deep venous thrombosis. Arch Intern Med 2002;162: 1144-8.
Hirsh J, Lee AY. How we diagnose and treat deep vein thrombosis. Blood 2002;99: 3102-10.(Paolo Prandoni, associate)
Correspondence to: P Prandoni paoloprandoni@tin.it
Introduction
Symptomatic deep vein thrombosis of the arm carries a low risk of recurrent thromboembolism. Post-thrombotic sequelae occur in almost one fourth of patients within the first two years and are related to residual thrombosis and, to a lesser degree, to the extent of the initial thrombosis. The rates of recurrent thromboembolism and post-thrombotic syndrome are lower than those observed in cohorts of patients with venous thrombosis of the leg.4 Whether the incidence of long term sequelae might be further reduced by physical devices or other methods is worth investigating.
An additional table showing outcomes in patients with and without vein catheters is on bmj.com
This article was posted on bmj.com on 15 July 2004 http://bmj.com/cgi/doi/10.1136/bmj.38167.684444.3A
Contributors: PP, AWAL, AG, and EB conceived and designed the study. PP, AWLA, MHP, and EB drafted the article. MHP and AM offered their statistical expertise for analysing and interpreting data. PP, SV, PB, DS, AP, and PS provided study patients and collected data by following them prospectively over years. AG, AP, AM, and PS critically reviewed the article for important intellectual content. All authors approved the final version of the article. PP is guarantor.
Funding: None.
Competing interests: None declared.
Ethical approval: Institutional Review Board of Padua University.
References
Prandoni P, Polistena P, Bernardi E, Cogo A, Casara D, Verlato F, et al. Upper extremity deep-vein thrombosis risk factors, diagnosis, and complications. Arch Int Med 1997;157: 57-62.
Kommareddy A, Zaroukian MH, Hassouna HI. Upper extremity deep venous thrombosis. Semin Thromb Hemost 2002;28: 89-99.
Prandoni P, Lensing AWA, Cogo A, Cuppini S, Villalta S, Carta M, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996;125: 1-7.
Kahn SR, Hirsch A, Shrier I. Effect of post-thrombotic syndrome on health-related quality of life after deep venous thrombosis. Arch Intern Med 2002;162: 1144-8.
Hirsh J, Lee AY. How we diagnose and treat deep vein thrombosis. Blood 2002;99: 3102-10.(Paolo Prandoni, associate)