大肠癌中nm23-H1的表达及其与临床病理特征的关系
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杨冬冬, 田素礼, 于金玲
大肠癌;nm23-H1;免疫组化杨冬冬,田素礼,于金玲.大肠癌中nm23-H1的表达及其与临床病理特征的关系. 世界华人消化杂志2007;15(4)412-415,杨冬冬,田素礼,于金玲,通讯作者:,电话:,收稿日期:,接受日
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杨冬冬, 田素礼, 于金玲, 哈尔滨医科大学附属第四医院普外二科 黑龙江省哈尔滨市 150001
通讯作者: 田素礼, 150001, 黑龙江省哈尔滨市南岗区颐圆街37号, 哈尔滨医科大学附属第四医院普外二科. yangdongdong02@163.com
电话: 0451-82576682
收稿日期: 2006-11-09 接受日期: 2006-12-01
Expression of nm23-H1 and its relationship with clinicopathological characteristics in human colorectal carcinoma
Dong-Dong Yang, Su-Li Tian, Jin-Ling Yu
Dong-Dong Yang, Su-Li Tian, Jin-Ling Yu,Department of General Surgery, the Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Correspondence to:Su-Li Tian, the Second Department of General Surgery, the Fourth Affiliated Hospital of Harbin Medical University, 37 Yiyuan Street, Nangang District, Harbin 150001, Heilongjiang Province, China. yangdongdong02@163.com
Received:2006-11-09Accepted:2006-12-01
AbstractAIM: To investigate the expression of nm23-H1 and its correlation with the clinicopathological characteristics in human colorectal carcinoma, and to explore the role of nm23-H1 expression in the carcinogenesis, development and metastasis of colorectal carcinoma.
METHODS: S-P immunohistochemical technique was used to detect the expression of nm23-H1 in 63 cases of colorectal cancer (including cancer and cancer-adjacent tissues), 16 cases of adenoma and 25 cases of normal colorectal tissues.
RESULTS: The level of nm23-H1 expression was significantly lower in colorectal cancer tissues than that in cancer-adjacent, normal mucosal or adenoma tissues (58 ......
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