[摘要]目的: 观察氨茶碱和纳洛酮治疗早产儿原发性呼吸暂停的临床效果。 方法: 50例患儿随机分为两组，治疗组25例在应用氨茶碱的基础上加用纳洛酮，对照组25例单用氨茶碱。 结果: 治疗组和对照组患儿的呼吸暂停次数分别为为(1.8±0.2)次.d、(3.4±1.2)次.d，治疗组明显减少(P<0.001)。治疗组和对照组患儿的呼吸暂停时间分别为(18.9±3.1)s、(23.2±2.5)s，治疗组明显缩短(P<0.05)。治疗组和对照组患儿呼吸暂停时SpO 2 下降程度及心率减慢程度分别为(83.0±8.4)%和(75.7±5.2)%、(95.3±12.8)次.min和(86.6±13.5)次.min(P均<0.05)。治疗组总有效率92.0%，对照组总有效率68.0%(P<0.05)。 结论: 氨茶碱和纳洛酮联合治疗早产儿原发性呼吸暂停比单用氨茶碱效果好，值得临床推广。

    [关键词] 氨茶碱;纳洛酮;原发性呼吸暂停;早产儿

    The clinical benefits of aminophylline plus naloxone on primary apnea in premature infants FENG Yu-ying (Yangquan Coal Group General Hospital，Shanxi Yangquan 045000，China)

    [Abstract] Objective:To observe the clinical benefits of aminophylline plus naloxone in treatment of primary apnea of premature infants.Meth-ods:50cases were divided into treatment group and contrast group.25cases were in the treatment group ......