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编号:11375373
异位宁对子宫内膜异位症大鼠血清白介素2及白介素10作用的实验研究
http://www.100md.com 《时珍国医国药》 2006年第11期
异位宁;,白介素2;,白介素10,,异位宁;,白介素2;,白介素10,1器材,2方法,3结果,4讨论,参考文献:
     摘要:目的通过研究异位宁对子宫内膜异位症大鼠血清IL-2、IL-10的影响来阐述异位宁的作用机理。方法采用自体子宫组织块移植法建立子宫内膜异位症大鼠模型。应用ELISA的方法,检测大鼠异位子宫内膜IL2,IL10含量。结果异位宁高剂量组IL-2含量明显高于模型对照,有显著性差异(P<0.01);IL-10含量明显低于模型对照组,有显著性差异(P<0.01)。结论异位宁可以通过降低IL-10水平,而升高IL-2进而提高细胞免疫功能,从而达到治疗子宫内膜异位症的目的。

    关键词:异位宁; 白介素2; 白介素10

    The Effefct of Yiweining on the Contents of IL2 and IL10 in the Model Rat with Endometriosis

    QU Fan, MA Wenguang , YANG Dongxia, MA Baozhang

    (Heilongjiang University of TCM, Harbin, 150040 China)

    Abstract:ObjectiveTo clarify the effect of YWN in treating endometriosis through measuring the contents of IL2 and IL10. Methods Operational selftransplantation was applied in establishing animal models. Detection of IL2 and IL10 was conducted with ELISA. Results There existed significant difference in the contents of IL2 and IL10 between YWN group and control group.Conclusion YWN can functions well in curing EM through reducing IL10 level and increasing IL2 level.

    Key words:Yiweining (YWN); IL2; IL10

    子宫内膜异位症是妇科的常见疑难病 ......

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