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编号:11375367
仙人掌药用成分的提取及其镇痛作用的实验研究
http://www.100md.com 《时珍国医国药》 2006年第11期
仙人掌;,药用成分;,提取;,药理;,镇痛,,仙人掌;,药用成分;,提取;,药理;,镇痛,1材料,2方法,3结果,4讨论,参考文献:
     摘要:目的对仙人掌药用成分的提取工艺及镇痛作用进行探讨。方法 采用乙醇提取,醋酸乙酯等有机溶剂萃取,经硅胶柱层分离,得到淡黄色物质,并对该物质进行了化学定性分析和小鼠镇痛作用实验。结果经化学定性分析,表明这种药用成分中含有黄酮类物质,其镇痛作用与阿司匹林和生理盐水比较:扭体法χ2分别为5.19,9.68(P<0.05或0.001);温浴法P<0.01或P<0.001。结论仙人掌植物中含有黄酮类物质,对小鼠具有显著的镇痛作用。

    关键词:仙人掌; 药用成分; 提取; 药理; 镇痛

    Studies on Extraction and Analgesic Effect of Medicinal Components in Opuntia dillenii Haw

    WEI Guofeng , LI Zhenzhong, HUANG Zuliang, HE Youcheng

    (Youjiang Medical College of Nationalities, Baise 533000, China)

    Abstract:ObjectiveTo investigate the extract processing and the analgesic effect of medicinal components in Opuntia dillenii Haw.MethodsThe chemical quantitative analysis and the analgesic effect on mice were carried out on a primrose yellow material which was extracted by ethanol, ethyl acetate and chromatographically separated by silica gel column.ResultsA flavonoid chemical compound was found and the χ2 were 5.19( P< 0.05 or 0.01) in writhing tests(P< 0.01 or 0.001), 9.68 in lukewarm bath procedure while compared its analgesic effect with aspirin and normal saline.ConclusionObvious analgesic effect on mice is found in Opuntia dillenii Haw. ......

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