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痛泻要方加味联合黛力新治疗肠易激综合征60例
http://www.100md.com 何如锋
中药痛泻要方;黛力新;肠易激综合征,何如锋,通讯作者:,CombinationofTongxieYaofangJiaweiandDeanxitintreatmentofirritablebowelsyndrome:ananalysisof60cas
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     何如锋, 四川省内江市第一人民医院中西医结合科 四川省内江市 641000

    通讯作者:
何如锋, 641000, 四川省内江市中区沱中路31号, 内江市第一人民医院中西医结合科. scnjhrf118@sina.com

    电话: 0832-2100073 传真: 0832-2104571

    收稿日期: 2006-12-05 接受日期: 2007-01-11

    Combination of Tongxie Yaofang Jiawei and Deanxit in treatment of irritable bowel syndrome: an analysis of 60 cases

    
Ru-Feng He

    Ru-Feng He,
Department of Integrated Chinese and Western Medicine, the First People’s Hospital of Neijiang City, Neijiang 641000, Sichuan Province, China

    Correspondence to:
Ru-Feng He, Department of Integrated Chinese and Western Medicine, the First People’s Hospital of Neijiang City, Sichuan 31 Tuozhong Road, Middle District, Neijiang 641000, Sichuan Province, China. scnjhrf118@sina.com

    Received:
2006-12-05 Accepted:2007-01-11

    Abstract

    AIM: To observe the clinical efficacy of Tongxie Yaofang Jiawei (TYJ) combined with Deanxit in the treatment irritable bowel syndrome (IBS).

    METHODS: A total of 110 IBS patients were divided randomly into group A (n = 60) and B (n = 50), treated with TYF combined with Deanxit, and TYF alone, respectively, for a course of 1 month. The efficacy rate and adverse effect were observed in both groups.

    RESULTS: The total efficacy rates were 100% and 84% in group and B, respectively (P < 0.05). Single-symptom analysis showed that the efficacy rates for abdominal pain, abdominal distention and diarrhea were significantly higher in group A than those in group B (100%, 96%, 93% vs 88%, 81%, 81%; all P < 0.05), while there were no marked difference for constipation and mucous stool between the two groups (P > 0.05). No visible adverse effects were observed in group A.

    CONCLUSION: Chinese medicine TYJ combined with Deanxit can rapidly alleviate the symptoms of abdominal pain, abdominal distention and diarrhea, etc. so as to improve the clinical efficacy and reduce the adverse effect.

    Key Words: Tongxie Yaofang Jiawei; Deanxit; Irritable bowel syndrome

    He RF. Combination of Tongxie Yaofang Jiawei and Deanxit in treatment of irritable bowel syndrome: an analysis of 60 cases. Shijie Huaren Xiaohua Zazhi 2007;15(7):777-780

    摘要

    目的: 观察中药痛泻要方加味联合黛力新治疗肠易激综合征(IBS)的临床疗效. 

    方法: 将110例IBS患者随机分为观察组(n = 60)和对照组(n = 50), 分别采用中药痛泻要方加味联合黛力新及单用中药痛泻要方加味治疗1 mo. 观察两组有效率、不良反应. 

    结果: 观察组和对照组总有效率分别为100%, 84%(P<0.05). 腹痛、腹胀、腹泻单项症状总有效率观察组分别为100%, 96%, 93%, 而对照组分别为88%, 81%, 81%(P均<0.05); 便秘、黏液便总有效率观察组与对照组无显著差异(P>0.05). 观察组治疗期间未发现明显不良反应.

    结论: 中药痛泻要方加味联合黛力新能快速消除和改善患者腹痛、腹胀、腹泻等症状, 显著提高临床治疗效果, 无明显不良反应.

    关键词: 中药痛泻要方; 黛力新; 肠易激综合征

    何如锋. 痛泻要方加味联合黛力新治疗肠易激综合征60例. 世界华人消化杂志 2007;15(7):777-780

    0 引言

    肠易激综合征(IBS)是一种具有特殊生理病理基础的、独立的肠功能紊乱性疾病[1]. IBS可以发生于任何年龄, 以20-40岁青壮年居多, 男女之比1/2, 占消化门诊量的20%, 我国IBS患病率约占人群的15%[2]. 其临床表现呈多样性, 症状持续或反复发作而无特异性[3], 但以腹痛、腹胀、腹泻或便秘、黏液便及便后不尽感为主要表现 ......

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