Evaluation of the efficacy in treatment of acute urinary tract infection with gatifloxacin mesylate injection

    WANG Hanª²Min, LIU Xiaoª²Wei, TAN Hua, XU Guoª²Shuang, SUN Shiª²Ren

    Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi¬ðan 710033, China

    ¡¾Abstract¡¿ AIM: To evaluate the efficacy and safety of gatifloª²xacin mesylate injection for acute urinary tract infection. METHODS: Fortyª²eight patients with acute urinary tract infection were randomly divided into 2 groups and given an injection of gatifloxacin mesylate and hydrochloric acid levofloxacin respectively. The efficacy and the adverse reaction were observed.RESULTS: The rate of clinical efficacy, the bacterial clearance rate, the bacterial sensitivity rate and the incidence of adverse reaction were 91%, 90%, 100% and 20% respectively in gatifloxacin mesylate injection group, and 88%, 86%, 100% and 24% respectively in hydrochloric acid levofloxacin injection group. There was no statistically significant differences in clinical efficacy and incidence of adverse reaction between the 2 groups (P>0.05). CONCLUSION: Gatifloxacin mesylate injection has favorable clinical efficacy and tolerance and safety for acute urinary tract infection, and it can be used as an elective drug to treat acute urinary tract infection caused by common sensitive bacteria. ......