牛蒡子；牛蒡苷；正交设计____

正交实验优化牛蒡子的提取工艺

http://www.100md.com 《儿科药学杂志》 2000年第1期

牛蒡子；牛蒡苷；正交设计,,],牛蒡子；牛蒡苷；正交设计,[关键词]牛蒡子；牛蒡苷；正交设计,1仪器与材料,2含量测定方法,3牛蒡子提取方法的选择,4讨论,参考文献：

     [摘要] 目的：优选牛蒡子乙醇提取的最佳工艺。方法：采用L9(34)正交试验筛选醇提工艺条件，用HPLC法测定牛蒡苷的含量。结果：牛蒡子的最佳醇提条件为：乙醇浓度70%，加8倍溶剂量，回流3次，回流时间1 h。结论：采用本工艺牛蒡子的活性成分牛蒡苷提取率达95.43%，工艺可行。

    [关键词] 牛蒡子；牛蒡苷；正交设计

    Optimization of the technology of extracting chemical constituents from fructus arctii by orthogonal experimental design

    LU Laichun, ZHANG Rong, ZHOU Shiwen, et al

    (Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, China)

    [Abstract] Objective:To optimize the technology of extracting chemical constituents from fructus arctii. Methods: HPLC was used to analyze the content of Arctinin, and the L9 (34) orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology. Results: The conditions of the ethanol extraction technology of extracting the constituents from Fructus arctii were 70 % ethanol, 1 hour of reflux, 8fold solvent and 3 times of extraction. Conclusions: With the extraction rate of arctiin as 95.43%, the optimized technology is stable and practical and worthy of a trial in pharmaceutical production. ......

百拇医药网 http://www.100md.com/html/DirDu/2007/03/23/40/08/65.htm

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