【摘要】 目的 研究药食两用植物枸杞果防治大鼠脂肪肝的效果。方法 成年wistar大鼠随机分为阴性对照组、模型组、枸杞果液低剂量组和高剂量组，实验处理持续5周，断头法处死大鼠并取血，测定血、肝生化指标及肝功能，观察肝组织病理变化。结果 模型组血清总胆固醇(TC)高于阴性对照组(P<0.05)，枸杞果液高剂量组血清TC低于模型组(P<0.05)；模型组肝组织TC、TG高于阴性对照组(P<0.05)，枸杞果液高剂量组肝组织TC低于模型组(P<0.05)。病理切片显示，枸杞果液高、低剂量组大鼠肝细胞脂肪变性较轻，炎细胞浸润轻于模型组。结论 枸杞果液能降低大鼠血清及肝组织的TC含量，减轻大鼠肝细胞脂肪变性程度。

    【关键词】 枸杞果 大鼠 脂肪肝

    Experimental Research of FRUCTUS LYCII on Preventing the Fatty Liver of Rat

    Sun Yaowu，et al.

    (The Public Health Department，Qiqihar Medical University,Heilongjiang Province 161042)

    【Abstract】 Objective To investigate the protective effect of FRUCTUS LYCII on the fatty liver of rat.Methods Wistar mature rats were divided into 4 groups randomly,which were normal control group，model control group，low and high dose group of FRUCTUS LYCII,5 weeks was continued,at the end of their treatment,they were killed.Some data had been collected such as the concentration of serum and liver total cholelterol(TC) and triglyceride(TG),the changes of liver pathological and so on.Results On the concentration of serum TC,model control group was significantly higher normal control group and high dose group of FRUCTUS LYCII was significantly different from model control group (P<0.05).0n the concentration of liver TC and TG ......