乳腺增生症；危险因素；病例-对照研究_

常州市女性乳腺增生症危险因素病例对照研究

http://www.100md.com 《中国公共卫生》 2007年第4期

乳腺增生症；危险因素；病例-对照研究,,乳腺增生症；危险因素；病例-对照研究,1对象与方法,2结果,3讨论,参考文献

     摘要：目的分析常州市女性乳腺增生症的危险因素，为该病防治提供科学依据。方法选取2005年7月1日～10月30日常州市钟楼区妇女病普查项目中确诊的乳腺增生症新发患者309名，按年龄匹配健康对照323名，用非条件Logistic多因素模型进行分析。结果 5年前体质指数>226kg/m2、使用过止乳针或药、良性乳腺疾病家族史、胸透或拍过X光片和本人是早产儿的OR值分别为187(95%CI＝115～303)，218(95%CI＝119～401)，377(95%CI＝207～689)，188(95%CI＝116～305)和226(95%CI＝104～489)；活产次数多、新鲜蔬菜年摄入量>1095kg和饮茶年数>20年的OR值分别为013(95%CI＝002～082)，046(95%CI＝026～081)和033(95%CI＝012～089)。结论常州市女性乳腺增生症的发生与5年前体质指数大、使用过止乳针或药、良性乳腺疾病家族史和胸透或拍过X光片等有关，经常摄入新鲜蔬菜及饮茶是保护因素。

    关键词：乳腺增生症；危险因素；病例-对照研究

    A case-control study on risk factors of hyperplasia of mammary gland in Changzhou city

    ZHU Yan,CHEN Yayu,QIAN Aizhen,et al.

    Health Care Center of Women and Children in Zhonglou District(Changzhou 213000,China)

    Abstract： Objective A case-control study was conducted to explore the risk factors of hyperplasia of mammary gland in Changzhou city，Jiangsu province.Methods 309 new cases diagnosed hyperplasia of mammary gland and 323 controls matched by age frequency in the body examination of gynaecology in the Health Care Center of Women and Children of Zhonglou district,Changzhou city were investigated by in-person interview during 1st,July and 30th,October,2005.Non-conditional Logistic regression model analysis was used to find the significant risk factors of hyperplasia of mammary gland.Results The BMI more than 226kg/m2 5 years ago,having taken anti-latic excreting medicine or injection,,family history of hyperplasia of mammary gland,X-ray exposure,premature were the risk factors of hyperplasia of mammary gland.Compared to the baseline group,the odd ratios(ORs) were 187(95%CI：115～303),218(95%CI：119～401),377(95%CI：207～689),188(95%CI：116～305)and 226(95%CI：104～489)respectively；more number of living birth,intake more vegetable and green tea were the protective factors for the hyperplasia of mammary gland,the ORs were 013(95%CI：002～082),046(95%CI：026～081)和033(95%CI：012～089).Conclusion BMI more than 226kg/m2 5 years ago,having taken anti-latic excreting medicine or injection,family history of hyperplasia of mammary gland,X-ray exposure and premature of herself were associated with increased risk of hyperplasia of mammary gland.More number of living birth ,intake more fresh vegetables and green tea may decrease risk of hyperplasia of mammary gland. ......

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