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竹节参总皂苷抑制小鼠肿瘤生长的实验研究
http://www.100md.com 《时珍国医国药》 2007年第2期
竹节参;,肿瘤;,小鼠,,竹节参;,肿瘤;,小鼠,1材料与方法,2结果,3讨论,参考文献:
     摘要:目的研究竹节参总皂苷对小鼠肿瘤模型的影响。方法以小鼠移植性肉瘤和腹水瘤为模型,观察竹节参总皂苷对小鼠肿瘤生长的抑制作用及对荷瘤小鼠生命延长期的影响。结果竹节参总皂苷能明显抑制小鼠移植性肉瘤S180的生长,延长H22腹水小鼠的生存时间。结论竹节参总皂苷具有较显著的抗肿瘤作用。

    关键词:竹节参; 肿瘤; 小鼠

    Effects of Total Saponins of Panax japonicus(TSPJ) on Tumor Growth in Mice

    YUAN Ding, ZUO Rui, ZHANG Changcheng

    (The Medical College of Three Gorges University, Yichang, Hubei 443002, China; Hubei Provincial Key Laboratory of Natural Products Research and Development, Yichang, Hubei 443002, China)

    Abstract:ObjectiveTo study the effects of saponins of Panax japonicus(TSPJ) on tumor model mice.MethodsWe used the mice with sarcoma S180 and with hepatoma H22 as models to observe the effect of TSPJ on mice tumor inhibition and the life prolongation respectively.ResultsWhen treated with TSPJ, the growth of the tumor in the mice with S180 was significantly inhibited and the life-span of the mice with H22 was prolonged.ConclusionTSPJ has significant effect of anti-tumor.

    Key words:TSPJ; Tumor; Mice

    竹节参Panax japonicus为五加科人参属植物[1] ......

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