消化液；_胃黏膜；_五磨饮子_____消化液；

五磨饮子促进大鼠胃液分泌及保护胃黏膜等作用的实验研究

http://www.100md.com 《时珍国医国药》 2007年第3期

消化液；,胃黏膜；,五磨饮子,,消化液；,胃黏膜；,五磨饮子,1材料与方法,2结果,3讨论,参考文献：

     摘要：目的观察五磨饮子对大鼠胃液分泌、胃黏膜保护等作用。方法采用Shay方法造成大鼠胃溃疡模型，观察灌服五磨饮子、思密达、生理盐水后大鼠胃液分泌总量、胃内总酸度、胃蛋白酶活性、损伤指数、溃疡发生率等指标的变化。结果五磨饮子与思密达均可明显促进胃液分泌(P<0.01) ，五磨饮子可明显提高胃酸分泌、明显抑制胃蛋白酶活性(P<0.01)，思密达不影响胃酸分泌、不影响胃蛋白酶活性(P>0.05)，五磨饮子、思密达均可降低Shay大鼠的损伤发生率，均有保护胃黏膜作用,五磨饮子保护胃黏膜作用较思密达为优。结论五磨饮子具有促进大鼠胃液分泌，抑制胃蛋白酶活性，保护胃黏膜等作用。作用机理可能与兴奋迷走神经、增加胃黏膜血流量有关。

    关键词：消化液；胃黏膜；五磨饮子

    Experimental Study of Wumo Decoction on Improving Gastric Juice Excretion and Protecting Gastric Mucosa in Rats

    SHANG Deshi,LI Lejun, SHAO Zuyan

    (Lianyungang Hospital of TCM, Jiangsu Province 222004,China; Second Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China)

    Abstract：ObjectiveTo study the effects of Wumo Decoction on gastric juice excretion and gastric mucosa.MethodsThe gastric ulcer was induced by Skay method and total quantity of gastric juice excretion,total acidity in Protectctgon stomach,activity of pepsin,injury index,incidence rate of ulcer in rats were observed after administering Wumo Decoction,Smecta,Sodium Chloride, to the ulcer rats.ResultsWumo Decoction and Smecta both could increase the rat's secretion of gastric juice (P<0.01), Wumo Decoction could highly promote secretion of gastric acid,obviously inhibit activity of pepsin (P<0.01), Smecta tad on effect on gastric acid and activity of pepsin(P>0.05)Wumo Decoction and Smecta both could lower incidence rate of gastric injury in the Shay's rat ......

百拇医药网 http://www.100md.com/html/DirDu/2007/04/29/42/89/52.htm

您现在查看是摘要页，全文长 8934 字符。