[摘要] 目的 评价拜复乐(盐酸莫西沙星)治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)感染发作期的临床疗效和用药安全性。 方法 应用拜复乐(盐酸莫西沙星)400 mg口服,每天1次,疗程10～14天,观察拜复乐治疗效果、细菌清除率和不良反应。结果 42例患者治疗总有效率95.24%,细菌清除率92.3%,不良反应发生率4.76%。 结论 拜复乐治疗慢性阻塞性肺疾病感染发作期具有良好的临床细菌学疗效和安全性。

    [关键词] 拜复乐；慢性阻塞性肺疾病；疗效；安全性

    Observation on curative efficacy of moxifloxacin in patients with COPD

    XIE Xiao-peng.The Second Affiliated Hospital,Shantou University Medical College,Shantou 515041,China

    [Abstract] Objective To evaluate the curative and side effects of moxifloxacin for chronic obstructive pulmonary disease(COPD) in acute exacerbation period.Methods After the administration of moxifloxacin 400 mg once daily for 10 to 14 days,the curative effects,bacterial clear rate and side effect were observed. Results In 42 cases,the total effective rate,bacterial clear rate and side-effect rate were 95.24%,92.3% and 4.76%,respectively. Conclusion Moxifloxacin is effective and safe for the patients with COPD in acute exacerbation period. ......