纳洛酮治疗急性非麻醉药物中毒性昏迷的临床研究
作者：张在其
单位：418200 湖南省怀化市第二人民医院急诊科
关键词：纳洛酮；急性非麻醉性药物；中毒
浙江临床医学000109摘 要：目的：研究纳洛酮治疗急性非麻醉药物中毒性昏迷的临床效果。方法：将符合入选标准的98例患者随机分成治疗组53例与对照组45例，治疗组采用纳洛酮治疗，对照组采用传统疗法。结果：治疗组的浅、深昏迷苏醒时间、治愈率分别为9.25±1.87小时、15.88±1.36小时、96.23%；对照组浅、深昏迷苏醒时间、治愈率分别为14.43±1.51小时、21.43±2.64小时、75.56%。两组之间有非常显著差异性，P<0.01。结论：纳洛酮对急性非麻醉药物中毒性昏迷的治疗有确切疗效。
The Clinical Study in Treating Acute Non-anesthetic Poisoning Coma by Naloxone
Zhang Zaiqi
Abstract：Objective: To assess the clinical effects of Naloxone in the treatment of patients with acute nonnarcotic poisoning coma. Methods: Nintey eight patients with acute non-narcotic poisoning coma were randomized into Naloxone treated group (n=53) and conventional treatment group (n=45). Results: In Naloxone group ,the revival time for light and deep comatous patients were 9.25±1.87 hours and 15.88±1.36 hours respectively. The overall cure rate 96.23%. In conventional treatment group, the revival time were 14.33±1.51 hours and 21.43±2.64 hours respectively.The cure trate was 75.56%. The revival time and the cure rate were significantly different between these two groups (P<0.01). Conclusion: Naloxone is a safe and effevtice drug in treating patients with acute non-narcotic poisoning coma.
Keywords：Naloxone acute non-anesthetic poisoning
参考文献：
[1]陈新谦，金有豫主编.新编药物学.第14版.北京：人民卫生出版社，1998.1：612.
[2]孟庆林.纳洛酮的药理与临床应用研究.中国急救医学，1994，14(1)：封2., http://www.100md.com
单位：418200 湖南省怀化市第二人民医院急诊科
关键词：纳洛酮；急性非麻醉性药物；中毒
浙江临床医学000109摘 要：目的：研究纳洛酮治疗急性非麻醉药物中毒性昏迷的临床效果。方法：将符合入选标准的98例患者随机分成治疗组53例与对照组45例，治疗组采用纳洛酮治疗，对照组采用传统疗法。结果：治疗组的浅、深昏迷苏醒时间、治愈率分别为9.25±1.87小时、15.88±1.36小时、96.23%；对照组浅、深昏迷苏醒时间、治愈率分别为14.43±1.51小时、21.43±2.64小时、75.56%。两组之间有非常显著差异性，P<0.01。结论：纳洛酮对急性非麻醉药物中毒性昏迷的治疗有确切疗效。
The Clinical Study in Treating Acute Non-anesthetic Poisoning Coma by Naloxone
Zhang Zaiqi
Abstract：Objective: To assess the clinical effects of Naloxone in the treatment of patients with acute nonnarcotic poisoning coma. Methods: Nintey eight patients with acute non-narcotic poisoning coma were randomized into Naloxone treated group (n=53) and conventional treatment group (n=45). Results: In Naloxone group ,the revival time for light and deep comatous patients were 9.25±1.87 hours and 15.88±1.36 hours respectively. The overall cure rate 96.23%. In conventional treatment group, the revival time were 14.33±1.51 hours and 21.43±2.64 hours respectively.The cure trate was 75.56%. The revival time and the cure rate were significantly different between these two groups (P<0.01). Conclusion: Naloxone is a safe and effevtice drug in treating patients with acute non-narcotic poisoning coma.
Keywords：Naloxone acute non-anesthetic poisoning
参考文献：
[1]陈新谦，金有豫主编.新编药物学.第14版.北京：人民卫生出版社，1998.1：612.
[2]孟庆林.纳洛酮的药理与临床应用研究.中国急救医学，1994，14(1)：封2., http://www.100md.com