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非洛地平缓释片对高血压病的疗效观察
http://www.100md.com 《四川生理科学杂志》 2000年第1期
     作者:饶莉 张庆 黄鹤

    单位:华西医科大学附属第一医学院心内科 成都 61004

    关键词:非洛地平缓释片;高血压;左室舒张功能

    四川生理科学杂志000111非洛地平缓释片对高血压病的疗效观察

    摘 要:目的:观察非洛地平缓释片对高血病的降压疗效及对心室舒张功能的影响。方法:30例高血压病患者,采用自身对照法,每天5mg,每日1次,连用4周。结果:收缩压下降4.4±0.9kpa,舒张压下2.51.okpa,均P
    The Study of the Clinical Curative Effects of Felodipine Extended-release Tablets
, 百拇医药
    Zeng Huanqong ,Liu Xingbin ,Rao Li ,Zhang Qing ,Huang He

    (The department of cardiology, the first hospltal of WCUMS Chengdu 610044)

    Abstract:To study the hypotension action and the effects of ventricular diastole of extended-release felodipinetablets. Method: we employed a self-crossover study to learn 30 patients of hypertension with felodipine tablets 5mg once a day for 4 weeks, then analyzed the results statistically. Results: The systolic and the diastolic pressure of the patients decreased by 4.4 0.9kPa and 2.5 1.0kPa respectively, compared with those without using felodipine( P< 0.05). 50% of the patients was improved and 40% effective. The overall effective rate was 90%. Parameters of ventricular diastole: the Emax of the electrdiograms of the patients was increased by 7%, while the A, A/E and DT decreased by 13.2 %, 18.7 % and 17.4 % respectively, compared with those without using felodipine (P < 0.01 ).C0nclusion: felodipine can decrease the blood pressure and improve the diastolic functions of the heart ventricles.
, 百拇医药
    Keywords:felodipine extended release tablet; hypertension; the diastolic functions of left ventricles

    作者单位:非洛地平缓释片对高血压病的疗效观察(华西医科大学附属第一医学院心内科 成都 610041)

    参考文献:

    [1]Todd PA, Funlds D、Felocdipine, A reiew Of the pharmacology and therapeutie use of the exlended release formulation in cardiovascuIar disorders.Drugs,1992;44;251

    [2]Dianzunmba SB et al. Left ventricular filling characterisistics in mild untreated hypertension.Hypertension,1986;8:156
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    [3]Snider AR,et al DOPPIer evaluation of left ventricular diastolic fillung in children with systemic hypertension Amm J cardiol,1985:56:921

    [4]Giren AR,et al.Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systoluc fuctuon.arch Intern Med,1985;145;281

    [5]王莉,等.早期高血压病心功能改变特点及硫氮 酮的影响.中华心血管病杂志,1989;17:338, 百拇医药